Selected Publications

  1. Hurley-Novatny A, Chang D, Murakami K, Wang L and Li H (2024) Poor bone health in Duchenne muscular dystrophy: a multifactorial problem beyond corticosteroids and loss of ambulation. Front. Endocrinol. 15:1398050. doi: 10.3389/fendo.2024.1398050
  2. Wang L*, Rochon ER, Gingras S, Zuchelkowski BE, Sinchar DJ, Alipour E, Reisz JA, Yang M, Page GP, Kanias T, Triulzi DJ, Lee JS, Kim-Shapiro DB, D'Alessandro A, Gladwin MT*. Functional effects of an African glucose-6-phosphate dehydrogenase (G6PD) polymorphism (Val68Met) on red blood cell hemolytic propensity and post-transfusion recovery. Transfusion. 2024 Feb 23;. doi: 10.1111/trf.17756. [Epub ahead of print] PubMed PMID: 38400625. (*Corresponding author)
  3. Amorim T, Trivanovic D, Benova A, Li H, Tencerova M, Palmisano B. Young minds, deeper insights: a recap of the BMAS Summer School 2023, ranging from basic research to clinical implications of bone marrow adipose tissue. Biol Open. 2024 Feb 15;13(2). doi: 10.1242/bio.060263. Epub 2024 Jan 30. PubMed PMID: 38288785; PubMed Central PMCID: PMC10855210.
  4. Donnenberg AD, Kim-Shapiro DB, Kanias T, Moore LR, Kiss JE, Lee JS, Xiong Z, Wang L, Triulzi DJ, Gladwin MT. Optimizing interpretation of survival studies of fresh and aged transfused biotin-labeled RBCs. Transfusion. 2023 Jan;63(1):35-46. doi: 10.1111/trf.17192. Epub 2022 Dec 9. PubMed PMID: 36494878; PubMed Central PMCID: PMC10069561.
  5. Xu Q, Rose JJ, Chen X, Wang L, DeMartino AW, Dent MR, Tiwari S, Bocian K, Huang XN, Tong Q, McTiernan CF, Guo L, Alipour E, Jones TC, Ucer KB, Kim-Shapiro DB, Tejero J, Gladwin MT. Cell-free and alkylated hemoproteins improve survival in mouse models of carbon monoxide poisoning. JCI Insight. 2022 Nov 8;7(21). doi: 10.1172/jci.insight.153296. PubMed PMID: 36173682; PubMed Central PMCID: PMC9675481.
  6. Hazegh K, Fang F, Kelly K, Sinchar D, Wang L, Zuchelkowski BE, Ufelle AC, Esparza O, Davizon-Castillo P, Page GP, Kanias T. Erythrocyte mitogen-activated protein kinases mediate hemolytic events under osmotic and oxidative stress and in hemolytic diseases. Cell Signal. 2022 Nov;99:110450. doi: 10.1016/j.cellsig.2022.110450. Epub 2022 Aug 25. PubMed PMID: 36029940; PubMed Central PMCID: PMC9530026.
  7. Crum R, Hall K, Molina C, Hussey G, Graham E, Li H, Badylak S. Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis. NPJ Regenerative Medicine, 2022. PMID: 35110573.
  8. Cramer M, Chang J, Li H, Serrero A, El-Kurdi M, Cox M, Schoen F, Badylak S. Tissue response, macrophage phenotype, and intrinsic calcification induced by cardiovascular biomaterials: Can clinical regenerative potential be predicted in a rat subcutaneous implant model? Journal of Biomedical Materials Research, 2022. PMID: 34323360.
  9. Li H*, Lu A, Gao X, Tang Y, Ravuri S, Wang B, Huard J*. Improved bone quality and bone healing of dystrophic mice by parabiosis. Metabolites, 2021,11 (4), 274. PMID: 33923553. (*Corresponding author)
  10. Sun H, Sherrier M, Li H*. Skeletal Muscle and Bone-Emerging Targets of Fibroblast Growth Factor-21. Frontiers Physiology, 2021, March;12:625287. PMID: 33762965. (*Corresponding author)
  11. Song X, Li H, Gao W. MyoMonitor: Evaluating Muscle Fatigue with Commodity Smartphones. Smart Health, 2021, 19, 100175.
  12. Zhao J, Zhang L, Lu A, Han Y, Colangelo D, Bukata C, O’Kelly R, Li H, Vo N, Huard J, Niedernhofer L, Robbins P. ATM is a key deriver of NF-kB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. Aging (Albany NY), 2020, 12 (6): 4688-4710. PMID: 32201398. 
  13.  Zuchelkowski BE, Wang L, Gingras S, Xu Q, Yang M, Triulzi D, Page GP, Gordeuk VR, Kim-Shapiro DB, Lee JS, Gladwin MT. Brief Report: Hydroxychloroquine does not induce hemolytic anemia or organ damage in a "humanized" G6PD A- mouse model. PLoS One. 2020;15(10):e0240266. doi: 10.1371/journal.pone.0240266. eCollection 2020. PubMed PMID: 33007039; PubMed Central PMCID: PMC7531777.
  14. Patel A, Zaky SH, Li H, Schoedel K, Amarza, A, Sfeir C, Sant S. Bottom-up self-assembled hydrogel-mineral composites regenerate rabbit ulna defect without added growth factors. ACS Applied Bio Materials, 2020, 3, 9, 5652-5663.
  15. Patel A, Zaky SH, Schoedel K, Li H, Sant V, Beniash E, Sfeir C, Sant S. Design and evaluation of collagen-inspired mineral-hydrogel nanocoposites for bone regeneration. Acta Biomaterialia, 2020, 112: 262-273. PMID: 32497742.
  16. Rose JJ, Bocian KA, Xu Q, Wang L, DeMartino AW, Chen X, Corey CG, Guimarães DA, Azarov I, Huang XN, Tong Q, Guo L, Nouraie M, McTiernan CF, O'Donnell CP, Tejero J, Shiva S, Gladwin MT. A neuroglobin-based high-affinity ligand trap reverses carbon monoxide-induced mitochondrial poisoning. J Biol Chem. 2020 May 8;295(19):6357-6371. doi: 10.1074/jbc.RA119.010593. Epub 2020 Mar 23. PubMed PMID: 32205448; PubMed Central PMCID: PMC7212636.
  17. Li H*, Sun H, Qian B, Feng W, Carney D, Miller J, Hogan MV, Wang L. Increased Expression of FGF-21 Negatively Affects Bone Homeostasis in Dystrophin/Utrophin Double Knockout Mice. J Bone Miner Res. 2020 Apr;35(4):738-752. doi: 10.1002/jbmr.3932. Epub 2019 Dec 30. PubMed PMID: 31800971. (*Corresponding author)
  18. Wang L*, Sparacino-Watkins CE*, Wang J, Wajih N, Varano P, Xu Q, Cecco E, Tejero J, Soleimani M, Kim-Shapiro DB, Gladwin MT. Carbonic anhydrase II does not regulate nitrite-dependent nitric oxide formation and vasodilation. Br J Pharmacol. 2020 Feb;177(4):898-911. doi: 10.1111/bph.14887. Epub 2019 Dec 23. PubMed PMID: 31658361; PubMed Central PMCID: PMC7024708.(*Corresponding author)
  19. Sherrier M, Li H*. The impact of keto-adaptation on exercise performance and the role of metabolic-regulating cytokines. The American Journal of Clinical Nutrition, 2019, 110(3): 562-573. PMID: 31347659 (*Corresponding author)
  20. Zhou S, Qian B, Wang L, Zhang C, Hogan M, Li H*. Altered bone-regulating myokine expression in skeletal muscle of Duchenne muscular dystrophy mouse models. Muscle & Nerve, 2018, 58(4): 573-582. PMID: 30028902. (*Corresponding author) 
  21. Azarov I*, Wang L*, Rose JJ*, Xu Q, Huang XN, Belanger A, Wang Y, Guo L, Liu C, Ucer KB, McTiernan CF, O'Donnell CP, Shiva S, Tejero J, Kim-Shapiro DB, Gladwin MT. Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning. Sci Transl Med. 2016 Dec 7;8(368):368ra173. doi: 10.1126/scitranslmed.aah6571. PubMed PMID: 27928027; PubMed Central PMCID: PMC5206801.(*Co-first author)
  22. Wright VJ, McCrum CL, Li H, Tranovich MJ, Huard J. Significant chondrocyte viability is present in acetabular chondral flaps associated with femoroacetabular impingement. The American Journal of Sports Medicine, 2017, 46(1): 149-152. PMID: 29024597.
  23. Li H*, Lu A, Tang Y, Beckman S, Nakayama N, Poddar M, Hogan, M, Huard, J*. The superior regenerative potential of muscle derived stem cells for articular cartilage repair is attributed to high cell survival and chondrogenic potential. Molecular Therapy - Methods & Clinical Development, 2016, 3: 16065. PMID: 27990446. (*Corresponding author)
  24. Li H*, Hicks J, Wang L, Oyster N, Philippon M, Hurwitz S, Hogan M, Huard J*. Customized platelet-rich plasma with transforming growth factor beta-1 neutralization antibody to reduce fibrosis in skeletal muscle. Biomaterials, 2016, 87: 147-156. PMID: 26923362. (*Corresponding author)
  25. Li H, Johnson N, Usas A, Lu A, Wang Y, Huard J. Sustained release of BMP2 via coacervate improves the osteogenic potential of muscle derived stem cells. Stem Cells Translational Medicine, 2013, 2 (9):667-77. PMID: 23884640.
  26. Li H, Usas A, Chen W, Poddar M, Huard J. Platelet-rich plasma promotes the proliferation of human muscle derived progenitor cells and maintains their stemness. PLOS ONE, 2013, 8(6): e64923. PMID: 23762264.
  27. Li H, Li B. PRP as a New Approach to Prevent Infection: Preparation and in vitro Antimicrobial Properties of PRP. Journal of Visualized Experiments, 2013, e50351, doi:10.3791/50351. PMID: 23609458.
  28. Li H, Hamza T, Tidwell J, Clovis N, and Li B. Unique antimicrobial effects of platelet-rich plasma and its efficacy as a prophylaxis to prevent implant-associated spinal infection. Advanced Healthcare Materials, 2013, 2 (9):1277-84. PMID: 23447088.
  29. Isaac C, Wright A, Usas A, Li H, Tang Y, Mu X, Greco N, Dong Q, Huard J. Dystrophin and Utrophin “double knockout” dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities. J Orthop Res, 2013, 31(3), 343-9. PMID: 23097179. (Cover story)
  30. Mifune Y, Matsumoto T, Takayama K, Ota S, Li H, Meszaros LB, Usas A, Nagamune K, Gharaibeh B, Fu FH, Huard J. The effect of platelet-rich plasma on the regenerative therapy of muscle derived stem cells for articular cartilage repair. Osteoarthritis Cartilage, 2013, 21 (1): 175-85. PMID: 23041435.
  31. Gao X, Usas A, Lu A, Tang Y, Wang B, Chen C, Li H, Tebbets JC, Cummins JH, Huard J. BMP2 is superior to BMP4 for promoting human muscle derived-stem cell mediated bone regeneration in a critical size calvarial defect model. Cell Transplantation, 2013, 22 (12):2393-408. PMID: 23244588.
  32. Wang L, Frizzell SA, Zhao X, Gladwin MT. Normoxic cyclic GMP-independent oxidative signaling by nitrite enhances airway epithelial cell proliferation and wound healing. Nitric Oxide. 2012 May 15;26(4):203-10. doi: 10.1016/j.niox.2012.03.002. Epub 2012 Mar 8. PubMed PMID: 22425780; PubMed Central PMCID: PMC3854970.